Statin Intolerance: What Are the Symptoms?
The ACC Statin Intolerance App guides clinicians through the process of managing and treating patients who report muscle symptoms while on statin therapy. Clinicians can use the app to: Answer questions to evaluate possible intolerance to a patient's current statin prescription.
Lipitor is a statin. It reduces levels of triglycerides and “bad” LDL cholesterol in the blood and increases levels of “good” HDL cholesterol. Adverse effects include headaches, pain in the joint.
At the Cleveland Clinic, 72.5% of patients with prior statin intolerance were successfully rechallenged with a statin, with most of these patients taking the drug on a daily basis and a smaller.
Statins are one of the most commonly prescribed drugs in clinical practice. They are usually well tolerated and effectively prevent cardiovascular events. Most adverse effects associated with statin therapy are muscle-related. The recent statement of.
In clinical practice, statin intolerance limits effective treatment of patients at risk of, or with, cardiovascular disease. Knowledge of the most common adverse effects of statin therapy that might cause statin intolerance and the clear definition of this phenomenon is crucial to effectively treat patients with lipid disorders.
Although muscle symptoms may occur, true statin intolerance is uncommon. Given the benefits of statins in ASCVD risk reduction, clinicians should partner with the patient to gain a thorough symptom history and determine if he or she is truly statin intolerant.
The AHA places new emphasis on the fact that statin users may experience muscle pain because of the “nocebo” (Latin for “I will harm”) effect. That occurs when negative expectations and fears about statins’ risks—aroused by media reports, warnings in package inserts, word of mouth from statin users, and rumors on the internet—become a self-fulfilling prophecy.